همراه سلامت و درمان کشور
Your Advanced Healthcare Partner
تهران، خیابان آرژانتین
بلوار الوند، خ35، پلاک8
No8 , 35th St. , Alvand Blv.
Argentina St. , Tehran
واحد فروش :
88651948-9 021
Sales Deptartment :
88651948-9 021
شنبه - چهارشنبه : 8:30 - 16:30
پنجشنبه : 8:30 - 12:30
Saturday - Wednesday : 8:30 - 16:30
Thursday : 8:30 - 12:30

Eclipse Cyclotrons

The Siemens Eclipse™ family of PET cyclotrons is a comprehensive solution for radioisotope production. Eclipse Cyclotron is an 11 MeV, negative ion, single particle accelerator designed for clinical and commercial production and distribution of 18F radiotracers as well as other positron emitting radioisotopes such as 11C, 13N, 15O and 64Cu. The Eclipse product line includes Eclipse RD and HP.   

 Powerful, Flexible, Reliable

. Deep Valley Patented Single-coil Magnet Design with Lowest Radiation Fields in the Industry

. Flexible Design Targets

. Compact & Self-Shielded

. Automated System Control

. Ease of Serviceability

Features & Benefits

Powerful, Flexible, Reliable

Siemens Eclipse™ cyclotron, an 11 MeV negative ion single particle accelerator, produces Curie levels of positron emitting radioisotopes — 18F,11C, 13N and 15O. Its self-shielded, automated design offers you fast, easy and efficient production of PET radioisotopes. Higher energy cyclotrons produce more neutrons of higher energy, which in turn, increase activation of surrounding vault walls. This activation is minimized with the 11 MeV Eclipse. Using advanced technology, Eclipse targetry offers efficient production of PET isotopes with minimal use of enriched starting materials such as 18O water. Our systems offer high-yields with reliable uptime. When it comes to the production of radiotracers, we see the ability to be automated yet flexible as key to producing consistent high yields. So we have simplified the production process and this in turn reduces the workload on your staff.

Deep Valley Patented Single-coil Magnet Design with Lowest Radiation Fields in the Industry

Eclipse’s unique sector design, with a valley-to-hill gap ratio of 27:1, enables high-quality beam focusing. This means improved beam transmission, greater production yields and greatly reduced internal activation. Eclipse uses a patented single-coil magnet that dramatically reduces the system’s power consumption. High efficiency supports high production capabilities along with low operating costs

 

Flexible Design Targets

 

Target Carousel

Eclipse targets are designed to enable easy installation and removal, minimizing radiation exposure to service personnel. Changing targets does not require breaking the accelerator vacuum, contributing to the system’s excellent uptime. There are two target carousel formats available on Eclipse – Eclipse HP and Eclipse RD. Eclipse HP target carousel holds up to four high-volume targets per beam line capable of running at up to 60 µA. Eclipse RD target carousel holds up to eight low volume targets per beam line capable of running at up to 40 µA. Both systems support production of 18F [F-], 18F [F2], 15O [O2], 13N Ammonia and 11C [CO2], but Eclipse RD cannot be outfitted with solid targets for production of  64Cu Copper or 18F [F-] target bodies made of tantalum. Optional dual extraction further allows two target changers to be mounted and the capability to simultaneously produce two different isotopes or to double the quantity of a single isotope.

Compact & Self Shielded

 

Cyclotron (self-shielded)

Eclipse’s self-shielded system substantially reduces radiation levels without the expense and space required for a vault. The dose at room boundary (7.62 m × 7.62 m × 4.57 m height; 25 ft × 25 ft × 15 ft height) is <2.0 mR/hour. The Eclipse self-shield is an engineered containment system, including a negative pressure effluent containment, prompt radiation shielding and interlocked access control. This eliminates the cost of vault design for the facility. The system is also available without the self-shield for installation in existing vault spaces. The design of Eclipse cyclotron reduces decommissioning costs as well since the self-shield can easily be removed without demolition at decommissioning, further reducing total cost of ownership.

Automated System Control

All major systems on Eclipse are automatically controlled through a Windows® workstation. The control software incorporates an easy-to-use interface. The Eclipse control system also allows you to initiate production remotely and within minutes the system is ready to irradiate a target. You can easily control all functions of the cyclotron, which allows you to optimize performance.

Ease of Serviceability

Vertical mounting of the ion source and extraction mechanism provides easy access and reduced maintenance time. The extraction carousel’s multiple, long-lived stripping foils enable extended operation before service is required.

 

Technical Details

Eclipse HP Typical Target Performance at 60 µA:

. 3,500 mCi (129.5 GBq) 18F [F-] in 120 min with a single tantalum target bombardment

. 7,000 mCi (259.0 GBq) 18F [F-] in 120 min with dual tantalum target bombardment

. 525 mCi (19.4 GBq) 18F [F2] in 40 minutes

. 200 mCi (7.4 GBq) of 13N Ammonia in 10 minutes

. 2,300 mCi (85.1 GBq) 15O [O2] gas in 10 minutes

. 2,000 mCi (74.0 GBq) 11C [CO2] in 50 minutes with a specific activity of >25 Ci/umole (925 GBq/umole)

. Support for 64Cu Copper production

 Eclipse RD Typical Target Performance at 40 µA:

. 2,000 mCi (74.0 GBq) 18F [F-] in 120 min with a single silver target

. 4,000 mCi (148.0 GBq) 18F [F-] in 120 min with dual silver targets

. 400 mCi (14.8 GBq) 18F [F2] in 40 minutes

. 100 mCi (3.7 GBq) of 13N Ammonia in 10 minutes

. 2,000 mCi (74.0 GBq) 15O [O2] gas in 10 minutes

. 1,500 mCi (55.5 GBq) 11C [CO2] in 50 minutes with a specific activity of >25 Ci/umole (925 GBq/umole)

System Specifications

    . Energy: 11 MeV

    . Magnet: 4-sector azimuthally varying field, single strip coil

     ° Power: 3kW

     ° Mean Field: 12,000 Gaus (1.2 Tesla)

     ° Valley to Hill Gap Ratio: 27:1

     ° Magnetic Field @Room Boundary: <1 Gauss (<0.1 millitesla)

     . RF System: Four Dees

     ° Fundamental Mode: 72MHz

     ° Max. Amplifier Power: 10kW

     . Ion Source: Penning Ion Gauge

     ° Max. H-current: 2 mA

     . Beam Extraction: Carbon Foils

     ° # Foils/Carousel: 3

     ° Foil Lifetime: 10,000 µA-hr

     ° Beam Size: 10mm (HP)
     ° Beam Size: 8mm (RD)

     . Vacuum

     ° Standby Pressure: 5 x 10-7 Torr (6.7 x 10-5 Pa)
     ° Operating ressure: <1 x 10-5 Torr (<1.3 x 10-3 Pa)

     . Power Consumption

     ° Standby <7kW

     ° Operating 35 kW

     . Heat Rejection

     ° Air 52,000 BTU/hr (15.3 kW)

     ° Water 90,000 BTU/hr (26.4 kW)

     . Shielding

     ° Eclipse HP: ≤2.0 mR/hr (≤20 µSv/hr) total n+g @ 2×60µA at room boundary 
        (7.62 m × 7.62 m × 4.57 m height; 25 ft × 25 ft × 15 ft height)

     ° Eclipse RD: ≤2.0 mR/hr (≤20 µSv/hr) total n+g @ 2×40µA at room boundary 
        (7.62 m × 7.62 m × 4.57 m height; 25 ft × 25 ft × 15 ft height)

     . Operating temperature: 21°C ± 1°C (70°F ± 2°F)

     . Operating humidity: 40-55% non-condensing R.H.

     . Mains: 3/N/PE AC, 50/60 Hz ± 1 Hz

     . Voltage: 208 V ± 3%

     . Connection Value: minimum of 45 kVA

Dimensions

Cyclotron

     . Width: 150 cm (58.8 in)

     . Depth: 150 cm (58.8 in)

     . Height: 173 cm (68.0 in)

     . Weight: 10,450 kg (23,000 lbs)

Movable Shields (Two Sets)

     . Width: 240 cm (94.5 in)

     . Depth: 184 cm (72.5 in)

     . Height: 230 cm (90.5 in)

     . Weight: 13,455 kg (29,595 lbs)

Stationary Shields

     . Width: 66 cm (26.0 in)

     . Depth: 83 cm (32.5 in)

     . Height: 231 cm (91.0 in)

     . Weight: 2,585 kg (5,690 lbs)

Control Cabinets (1 unit)

     . Width: 142 cm (56.0 in)

     . Depth: 80 cm (31.5 in)

     . Height: 210 cm (82.5 in)

     . Weight: 1,000 kg (2,200 lbs)


Heat Exchange Cabinet

     . Width: 81 cm (32.0 in)

     . Depth: 80 cm (31.5 in)

     . Height: 210 cm (82.5 in)

     . Weight: 450 kg (1,000 lbs)